Urbana was founded in 1833. The city was founded by people coming from Ohio, who named it after the City of Urbana, Ohio.
Interestingly, according to Wikipedia, that city in Urbana was in turn named after a town in Virginia.
The town from Virginia is actually named "Urbanna" (notice the 2 n's in the name). According to the history page of the town's website:
The 1680 Acts of Assembly at Jamestown changed all that.
They ordered local officials to establish 20, 50-acre port towns, at a cost of 10,000 pounds of tobacco each, through which all trade would take place: Varina, Charles City, Surry, Jamestown, Patesfield, Nansemond and Warwick along with plantations in Elizabeth City, Norfolk, Yorktown, New Kent, Gloucester, Tappahannock, Stafford, Accomac, Northampton, Lancaster, Northumberland—and the small part of Ralph Wormeley’s Rosegill that would, in 1705, be named Burgh of Urbanna, “City of Anne.” The town was named in honor of England’s Queen Anne.
There you go ... the name Urbana is therefore linked to Queen Anne of England!!